1. Production of Water for Injection (WFI):
LVPs such as IV fluids (e.g., dextrose, saline, ringer’s lactate) require
WFI as their main solvent. Multi-column distillation systems produce
WFI in compliance with pharmacopeia standards (e.g., USP, EP, IP).
2. High Purity Assurance:
Multicolumn distillation ensures removal of:
Endotoxins (pyrogens)
Volatile and non-volatile impurities
Microbial contamination
The multiple-effect design improves efficiency while maintaining
extremely low conductivity and TOC levels.
3. Energy Efficiency:
Compared to single-effect distillation, multicolumn systems reuse
heat across stages, drastically reducing energy consumption—
essential for high-volume LVP production.
4. Continuous and Reliable Supply:
LVP production is high-throughput and continuous. Multicolumn
distillation systems are designed for uninterrupted operation to
match the demand for sterile WFI.
5. Regulatory Compliance & Validation:
These systems are validated to meet cGMP, FDA, and EU guidelines,
which is crucial for injectable-grade water used in parenterals.
Ravi Kiran Industries are leaders in manufacturing distillation columns since 1985.
